Review




Structured Review

BIOPAC systems software version- 4.3.1
Schematic showing the speculative mechanism of larger flush volume following low umbilical venous catheter (UVC) epinephrine in term newborns. During cardiac arrest (absence of spontaneous cardiac activity) and during chest compressions and positive pressure ventilation (PPV) that increase the intrathoracic pressure and cause back pressure in the inferior vena cava, the epinephrine injected via a low umbilical venous catheter followed by a low flush volume of 0.5 mL to 1 mL may not be delivered to the right atrium. The epinephrine may be deposited in the umbilical vein or hepatic veins. The use of a higher flush volume may propel the epinephrine to the right atrium and across the patent foramen ovale (PFO) to left heart, aorta, systemic circulation, and coronary arteries increasing the chances of return of spontaneous circulation <t>(ROSC).</t> Inset shows a magnified view of the heart and coronary vessels. The yellow line represents the path of epinephrine and flush in the figure and the inset. Copyright Satyan Lakshminrusimha.
Systems Software Version 4.3.1, supplied by BIOPAC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/systems+software+version-+4%2E3%2E1/systems+software+version++4+3+1/pmc08228479-57-10-14
Average 90 stars, based on 1 article reviews
systems software version- 4.3.1 - by Bioz Stars, 2026-09
90/100 stars

Images

1) Product Images from "Effect of a Larger Flush Volume on Bioavailability and Efficacy of Umbilical Venous Epinephrine during Neonatal Resuscitation in Ovine Asphyxial Arrest"

Article Title: Effect of a Larger Flush Volume on Bioavailability and Efficacy of Umbilical Venous Epinephrine during Neonatal Resuscitation in Ovine Asphyxial Arrest

Journal: Children

doi: 10.3390/children8060464

Schematic showing the speculative mechanism of larger flush volume following low umbilical venous catheter (UVC) epinephrine in term newborns. During cardiac arrest (absence of spontaneous cardiac activity) and during chest compressions and positive pressure ventilation (PPV) that increase the intrathoracic pressure and cause back pressure in the inferior vena cava, the epinephrine injected via a low umbilical venous catheter followed by a low flush volume of 0.5 mL to 1 mL may not be delivered to the right atrium. The epinephrine may be deposited in the umbilical vein or hepatic veins. The use of a higher flush volume may propel the epinephrine to the right atrium and across the patent foramen ovale (PFO) to left heart, aorta, systemic circulation, and coronary arteries increasing the chances of return of spontaneous circulation (ROSC). Inset shows a magnified view of the heart and coronary vessels. The yellow line represents the path of epinephrine and flush in the figure and the inset. Copyright Satyan Lakshminrusimha.
Figure Legend Snippet: Schematic showing the speculative mechanism of larger flush volume following low umbilical venous catheter (UVC) epinephrine in term newborns. During cardiac arrest (absence of spontaneous cardiac activity) and during chest compressions and positive pressure ventilation (PPV) that increase the intrathoracic pressure and cause back pressure in the inferior vena cava, the epinephrine injected via a low umbilical venous catheter followed by a low flush volume of 0.5 mL to 1 mL may not be delivered to the right atrium. The epinephrine may be deposited in the umbilical vein or hepatic veins. The use of a higher flush volume may propel the epinephrine to the right atrium and across the patent foramen ovale (PFO) to left heart, aorta, systemic circulation, and coronary arteries increasing the chances of return of spontaneous circulation (ROSC). Inset shows a magnified view of the heart and coronary vessels. The yellow line represents the path of epinephrine and flush in the figure and the inset. Copyright Satyan Lakshminrusimha.

Techniques Used: Activity Assay, Injection

Related Articles

Software:

Article Title: Effect of a Larger Flush Volume on Bioavailability and Efficacy of Umbilical Venous Epinephrine during Neonatal Resuscitation in Ovine Asphyxial Arrest
Article Snippet: Hemodynamic variables were continuously monitored during asphyxia, resuscitation and after ROSC, and recorded using BIOPAC systems (Goleta, CA, USA) software version- 4.3.1.

Activity Assay:

Article Title: Effect of a Larger Flush Volume on Bioavailability and Efficacy of Umbilical Venous Epinephrine during Neonatal Resuscitation in Ovine Asphyxial Arrest
Article Snippet: Hemodynamic variables were continuously monitored during asphyxia, resuscitation and after ROSC, and recorded using BIOPAC systems (Goleta, CA, USA) software version- 4.3.1.

Injection:

Article Title: Effect of a Larger Flush Volume on Bioavailability and Efficacy of Umbilical Venous Epinephrine during Neonatal Resuscitation in Ovine Asphyxial Arrest
Article Snippet: Hemodynamic variables were continuously monitored during asphyxia, resuscitation and after ROSC, and recorded using BIOPAC systems (Goleta, CA, USA) software version- 4.3.1.



Similar Products

90
BIOPAC systems software version- 4.3.1
Schematic showing the speculative mechanism of larger flush volume following low umbilical venous catheter (UVC) epinephrine in term newborns. During cardiac arrest (absence of spontaneous cardiac activity) and during chest compressions and positive pressure ventilation (PPV) that increase the intrathoracic pressure and cause back pressure in the inferior vena cava, the epinephrine injected via a low umbilical venous catheter followed by a low flush volume of 0.5 mL to 1 mL may not be delivered to the right atrium. The epinephrine may be deposited in the umbilical vein or hepatic veins. The use of a higher flush volume may propel the epinephrine to the right atrium and across the patent foramen ovale (PFO) to left heart, aorta, systemic circulation, and coronary arteries increasing the chances of return of spontaneous circulation <t>(ROSC).</t> Inset shows a magnified view of the heart and coronary vessels. The yellow line represents the path of epinephrine and flush in the figure and the inset. Copyright Satyan Lakshminrusimha.
Systems Software Version 4.3.1, supplied by BIOPAC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/systems+software+version-+4%2E3%2E1/systems+software+version++4+3+1/pmc08228479-57-10-14
Average 90 stars, based on 1 article reviews
systems software version- 4.3.1 - by Bioz Stars, 2026-09
90/100 stars
  Buy from Supplier

Image Search Results


Schematic showing the speculative mechanism of larger flush volume following low umbilical venous catheter (UVC) epinephrine in term newborns. During cardiac arrest (absence of spontaneous cardiac activity) and during chest compressions and positive pressure ventilation (PPV) that increase the intrathoracic pressure and cause back pressure in the inferior vena cava, the epinephrine injected via a low umbilical venous catheter followed by a low flush volume of 0.5 mL to 1 mL may not be delivered to the right atrium. The epinephrine may be deposited in the umbilical vein or hepatic veins. The use of a higher flush volume may propel the epinephrine to the right atrium and across the patent foramen ovale (PFO) to left heart, aorta, systemic circulation, and coronary arteries increasing the chances of return of spontaneous circulation (ROSC). Inset shows a magnified view of the heart and coronary vessels. The yellow line represents the path of epinephrine and flush in the figure and the inset. Copyright Satyan Lakshminrusimha.

Journal: Children

Article Title: Effect of a Larger Flush Volume on Bioavailability and Efficacy of Umbilical Venous Epinephrine during Neonatal Resuscitation in Ovine Asphyxial Arrest

doi: 10.3390/children8060464

Figure Lengend Snippet: Schematic showing the speculative mechanism of larger flush volume following low umbilical venous catheter (UVC) epinephrine in term newborns. During cardiac arrest (absence of spontaneous cardiac activity) and during chest compressions and positive pressure ventilation (PPV) that increase the intrathoracic pressure and cause back pressure in the inferior vena cava, the epinephrine injected via a low umbilical venous catheter followed by a low flush volume of 0.5 mL to 1 mL may not be delivered to the right atrium. The epinephrine may be deposited in the umbilical vein or hepatic veins. The use of a higher flush volume may propel the epinephrine to the right atrium and across the patent foramen ovale (PFO) to left heart, aorta, systemic circulation, and coronary arteries increasing the chances of return of spontaneous circulation (ROSC). Inset shows a magnified view of the heart and coronary vessels. The yellow line represents the path of epinephrine and flush in the figure and the inset. Copyright Satyan Lakshminrusimha.

Article Snippet: Hemodynamic variables were continuously monitored during asphyxia, resuscitation and after ROSC, and recorded using BIOPAC systems (Goleta, CA, USA) software version- 4.3.1.

Techniques: Activity Assay, Injection